Real Mushrooms, 5 Defenders Mushroom Blend Immune Strength, 1000 mg, 90 Caps

Think of 5 Defenders® as your mushroom “multivitamin.”

Whether you’re looking for daily wellness support or to maintain long-term health, this pure, organic blend of five functional mushrooms offers a natural and effective solution.

We have crafted a synergistic, optimal immune-supporting mushroom complex based on decades of research and traditional use. Each 5 Defenders® mushroom contributes its own distinct set of bioactive compounds, like beta-glucans, triterpenes, and antioxidants that target different aspects of immune and overall wellness support.

Suggested Use

Take 2 capsules daily with or without food, or as recommended by your healthcare professional.

Many customers find it easiest to incorporate 5 Denfenders® into their morning wellness routine, paired with other Real Mushrooms best-sellers like Lion’s Mane or Cordyceps.

Quality & Certifications

Real Mushrooms products are always:

• Rated the #1 Mushroom brand by ConsumerLab
• Made from USDA Certified Organic Mushrooms
• Verified for active compounds, safety, & purity through third-party testing
• Purity-IQ verified for authenticity using nuclear magnetic resonance
• Free of grains, starches, and fillers
• Sourced from mushroom (fruiting bodies) only—never mycelium fermented grain
• Produced in a Good Manufacturing Practices (GMP)-compliant facility

This is our Real Mushrooms Guarantee: no shortcuts, no gimmicks—just real mushrooms.

Balanced Immune Response

This mushroom complex is a blend of five extract powders: Reishi, Shiitake, Maitake, Turkey Tail mushrooms and Chaga. They are renowned for their naturally high levels of beta-glucans, polysaccharides that can help balance your body’s natural immune response.† Our extract is optimized to contain more than 20% beta-glucans, ensuring consistent, effective support in every serving.

Real Mushrooms, Not Filler

Most mushroom supplements fail because they’re made without mushrooms: they use mycelium fermented grain. Those products have few beneficial fungal compounds—they’re mostly starch.

We use 100% hot water-extracted mushrooms (fruiting body) to unlock the true full spectrum of beneficial compounds.

Highest-Quality, Organic Ingredients

We partner with experienced mushroom growers using Di Dao 地道 (spiritual homeland) cultivation practices to harvest mushrooms in their geo-authentic environments. Our 5 Defenders® contain only the real mushroom, grown, extracted, and tested with integrity.

FAQ

Where are your mushrooms from?

All our mushroom extracts are from the leading supplier of organic mushroom extracts: Nammex. They have over 40 years of mushroom growing experience and were one of the first companies to bring organic functional mushroom extracts to North America.

Their ingredients go through rigorous quality control and are tested twice for heavy metals, agricultural chemicals and microbial contamination to ensure they meet all standards for dietary supplements of this nature. All of their extracts are made from certified organic mushrooms (fruiting bodies), organically grown or wildcrafted from deep within mountain regions of China.

Mushrooms used for dietary supplements are seldom grown in North America since they are too expensive. China is the leading supplier of mushrooms worldwide and supplies over 90% of the world’s mushrooms.

It has a rich history of mushroom use as both food and medicine and is the birthplace of mushroom cultivation, with shiitake being farmed in the early 1200s. China is one of the only places in the world where you can get 100% organic mushroom (fruiting body) extracts that can be sold at an affordable price.

What is the difference between capsules and powder?

The products are identical. The only difference is how you want to consume them.

2 capsules is equivalent to roughly a 1/2 tsp of the mushroom powders.

In terms of potency and efficacy, both the capsules and powders are equally effective at delivering.

The capsules are great for travel, whereas the powder can be added to recipes or mixed in coffee, tea or bone broth.

Why do you use mushrooms and not mycelium?

It is extremely important to distinguish the difference between mushrooms and mycelium.

Mushrooms are the “fruit” and reproductive stage of these organisms, while the mycelium is the root system or “body” of the fungus.

Mushrooms contain much higher levels of active compounds like beta-glucans, and there is a large body of research on them. They have also been consumed for thousands of years as food, and many health benefits have been shown from just mushroom consumption.

Mycelium is commonly grown on a grain substrate, and this grain cannot be separated from the mycelium, so much of the final product is actually grain with no mushrooms present. This shows up in high amounts of starch and low amounts of active compounds like beta-glucans.

For these reasons, Real Mushrooms® only utilizes mushrooms in all of its products, with verified levels of important active compounds like beta-glucans, and is always guarded against starchy fillers like grain.

What are the benefits of 5 Defenders®?

5 Defenders® is a blend of organic mushroom extracts designed to help support overall well-being, resilience, and immune system health.

5 Defenders® is where most customers begin with Real Mushrooms®.

While single-mushroom supplements can be helpful for targeted needs, they often address just one slice of the wellness picture. Real Mushrooms®’ 5 Denfenders® blend, however, supports:

• Innate and adaptive immune function
• Oxidative stress resilience
• Calm, balanced energy
• Gut and microbiome health (through Turkey Tail’s prebiotic-like effects)

The blend is derived from 100% organic mushrooms, not myceliated grain, so you get potency without compromise: no starch, no fillers, just the active compounds your body can actually use.

What is the proportion of each ingredient in the 5 Defenders® mushroom complex?

5 Defenders® is a blend of extract powders consisting of:

• 30% Turkey Tail Mushroom
• 20% Reishi Mushroom
• 20% Shiitake Mushroom
• 20% Maitake Mushroom
• 10% Chaga

Why do the 5 Denfenders® mushroom capsules contain other ingredients?

Natural ingredients don’t always flow smoothly through processing equipment, and capsule manufacturers need to utilize other ingredients to fill capsules. It is common practice for encapsulation facilities to require the use of other ingredients.

We have worked closely with our encapsulation partners to ensure that only what is added is necessary to create the mushroom capsules.